diff --git a/lib/pleroma/web/pleroma_api/controllers/emoji_reaction_controller.ex b/lib/pleroma/web/pleroma_api/controllers/emoji_reaction_controller.ex
index 0933363a6..e762fcad8 100644
--- a/lib/pleroma/web/pleroma_api/controllers/emoji_reaction_controller.ex
+++ b/lib/pleroma/web/pleroma_api/controllers/emoji_reaction_controller.ex
@@ -41,6 +41,17 @@ def index(%{assigns: %{user: user}} = conn, %{id: activity_id} = params) do
     end
   end
 
+  defp filter_allowed_user_by_ap_id(ap_ids, excluded_ap_ids) do
+    Enum.reject(ap_ids, fn ap_id ->
+      with false <- ap_id in excluded_ap_ids,
+           %{is_active: true} <- User.get_cached_by_ap_id(ap_id) do
+        false
+      else
+        _ -> true
+      end
+    end)
+  end
+
   def filter_allowed_users(reactions, user, with_muted) do
     exclude_ap_ids =
       if is_nil(user) do
@@ -51,7 +62,7 @@ def filter_allowed_users(reactions, user, with_muted) do
       end
 
     filter_emoji = fn emoji, users, url ->
-      case Enum.reject(users, &(&1 in exclude_ap_ids)) do
+      case filter_allowed_user_by_ap_id(users, exclude_ap_ids) do
         [] -> nil
         users -> {emoji, users, url}
       end
diff --git a/test/pleroma/web/mastodon_api/controllers/status_controller_test.exs b/test/pleroma/web/mastodon_api/controllers/status_controller_test.exs
index 6f04975b8..30be34007 100644
--- a/test/pleroma/web/mastodon_api/controllers/status_controller_test.exs
+++ b/test/pleroma/web/mastodon_api/controllers/status_controller_test.exs
@@ -1960,6 +1960,10 @@ test "index" do
       {:ok, _} = CommonAPI.react_with_emoji(activity.id, other_user, "🎅")
       User.mute(user, other_user)
 
+      deactivated_user = insert(:user)
+      {:ok, _} = CommonAPI.react_with_emoji(activity.id, deactivated_user, "🎅")
+      User.set_activation(deactivated_user, false)
+
       result =
         conn
         |> get("/api/v1/statuses/?ids[]=#{activity.id}")
@@ -1967,6 +1971,7 @@ test "index" do
 
       assert [
                %{
+                 "emoji_reactions" => [],
                  "pleroma" => %{
                    "emoji_reactions" => []
                  }